Coffee With Scott Adams — Knowledge Archive October 12, 2026
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did you? That's right. And in order to enjoy the double-sided whiteboard to its full extent, what do you need? Not much. A coffee mug or a glass, a tankard, a chalice or a stein, a canteen, a jug or a flask, a vessel of any kind. And you can fill it with your favorite liquid. I'm partial to coffee. And join me now for the unparalleled pleasure of the dopamine hit of the day, the thing that makes…

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tter, 75 percent better. It's called the simultaneous sip. It happens now. Go.

I feel science becoming more accurate. I feel data starting to be credible. And that's just one sip. Imagine if I finish that entire mug. Oh yeah. Oh yeah.

All right, and we'll talk about the election and allegations of fraud in a moment, but some fun stories first. We have yet another potential vaccine that could make a big difference. Oxford-AZ, so AstraZeneca I guess. They've got a vaccine that has a strange story to it. Here's the strange story. It was a big old scientific trial and it was supposed to be two doses to each person. But they discovered after they had given a bunch of the first doses that the first doses had been, by mistake, half as much as they were supposed to be.

So then they said, well, what do we do now? Because we started this trial and the first doses are all the wrong amount. So they said, well, we can salvage it by at least giving the full dose on the second one and let's just see what happens. And what happened was it turns out, according to their initial data, I've got some questions about the accuracy of the data, but their data says that when they got a half dose followed, I think, a month later by a full dose, that they got to 90 percent efficiency of the vaccine. But when they did it the way they were supposed to do it, two full doses, it was only 60 percent as effective.

Now there are a few possible ways to explain this. Number one way, everything about this trial is wrong. Now, was there a point in this whole vaccine situation where you said to yourself, I'm feeling pretty good about science because scientists are killing it. You know, this whole warp speed thing, man, clap, clap, clap for our scientists around the world, not just in the United States but other countries too. And they're just killing it with this development of the vaccine. So science is something you can depend on. Except, wait, what was that thing you said to me, Scott, about science?

Did an entire randomized drug trial of the most important thing in the world that could be tested at this moment, coronavirus vaccine, and in the most important trial or one of the few for these vaccines, one of the most important trials in the world, maybe in all of civilization, and how many people had to look at that, whatever the directions were, how many people looked at that study before rolling it out to not know that they had somehow accidentally given everybody half a dose? Are you still really confident about your scientific process?

Because the trouble is that science as a system is terrific compared to other ways of understanding your reality. But unfortunately science is populated with people. And while we can all agree that science as a concept is pretty darn awesome, can we also agree that human beings as entities are pretty darn shitty? In fact, I could give you a pretty long list of how human beings work. Total crap. And unfortunately when you take a concept like science, which is terrific, really excellent, and you combine it with organic creatures who tend to be pretty shitty on average, you get something that's the average of something awesome, science, and something pretty shitty, people. So that's how you get half a dose.

So put that right in your arm, huh? Yeah. Let me shoot up with a vaccine that the best scientists in Great Britain couldn't figure out the difference between half a dose and a full dose. Yeah, I got a lot of confidence in that one. I think I'll take the American vaccine. That's just me. I think I'll take the American one. Not that it's necessarily better, by the way. I am pro-vaccination, just to be clear. I'm pro-vaccination. But it's always a tentative opinion, meaning I'd change it in a heartbeat if the data changes.

So I'm not going to make a personal decision about taking a vaccine, the coronavirus vaccine, any one of the different vaccines. I'm not going to make a personal decision until the last minute. If you're making a decision now instead of waiting for the last minute, you're doing it wrong because there might be new information. So you know, I'm not going to wait for people to take it then wait a year to see if they have any health problems. I probably won't do that. But I'm certainly going to wait as long as

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I can before I make a decision, just in case. I think that I'll probably take it. But here's the other interesting thing about this Oxford-AstraZeneca story. The accident may have discovered something that's really, really important, in the same way that yellow sticky notes were discovered by accident and I think penicillin was discovered by accident and a lot of things get discovered by accident…

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